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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">CC</journal-id>
<journal-id journal-id-type="nlm-ta">Cardiol Croat</journal-id>
<journal-title-group>
<journal-title>Cardiologia Croatica</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Cardiol. Croat.</abbrev-journal-title>
</journal-title-group>
<issn pub-type="ppub">1848-543X</issn>
<issn pub-type="epub">1848-5448</issn>
<publisher><publisher-name>Croatian Cardiac Society</publisher-name></publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">CC 10_9-10_238</article-id>
<article-id pub-id-type="doi">10.15836/ccar.2015.238</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Abstract</subject></subj-group>
</article-categories>
<title-group>
<article-title>Polyvascular atherosclerotic disease and multiple risk factors: focus on arterial hypertension</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-5374-0892</contrib-id><name><surname>Begic</surname><given-names>Alden</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">http://orcid.org/0000-0001-6937-1772</contrib-id><name><surname>Bico</surname><given-names>Amina</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-5111-9330</contrib-id><name><surname>Lekic</surname><given-names>Lana</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Tanovic</surname><given-names>Admir</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-7678-0344</contrib-id><name><surname>Bejtovic</surname><given-names>Demir</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">http://orcid.org/0000-0003-4864-2013</contrib-id><name><surname>Kulic</surname><given-names>Mehmed</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-7309-1455</contrib-id><name><surname>Dilic</surname><given-names>Mirza</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<aff id="aff1"><label>1</label>University Clinical Center Sarajevo, Sarajevo, Bosnia and Herzegovina</aff>
<aff id="aff2"><label>2</label>Faculty of Health Studies, Sarajevo, Bosnia and Herzegovina</aff>
</contrib-group>
<author-notes>
<corresp id="cor1">Address for correspondence: Alden Begic, Univerzitetski klinicki centar Sarajevo, Bolnicka 25, 71000 Sarajevo, Bosnia and Herzegovina. / Phone: +387-33-297209 / E-mail: <email xlink:href="aldenbegic@yahoo.com">aldenbegic@yahoo.com</email></corresp></author-notes>
<pub-date pub-type="ppub"><month>10</month><year>2015</year></pub-date>
<volume>10</volume>
<issue>9-10</issue>
<fpage>238</fpage>
<lpage>238</lpage>
<history>
<date date-type="received"><day>11</day><month>09</month><year>2015</year></date><date date-type="accepted"><day>17</day><month>09</month><year>2015</year></date>
</history>
<permissions>
<copyright-year>2015</copyright-year>
<copyright-holder>Croatian Cardiac Society</copyright-holder>
</permissions>
<kwd-group kwd-group-type="author"><title>KEYWORDS: </title><kwd>polyvascular atherosclerotic disease</kwd><kwd>arterial hypertension</kwd><kwd>multiple risk factors</kwd></kwd-group>
</article-meta>
</front>
<body>
<p>Introduction: The goal of this study is to evaluate the role of arterial hypertension (HTA) in patients (pts) with atherosclerotic disease (AthD) of coronary arteries (CAD), carotid arteries (CdA) and iliaco-femoro-popliteal (IFP) arteries. (<xref ref-type="bibr" rid="r1"><italic>1</italic></xref>-<xref ref-type="bibr" rid="r3"><italic>3</italic></xref>)</p>
<p>Patients and Methods: The study included a total of 311 pts with with clear clinical AthD. We evaluated the presence of CAD, CdA, and IFP as well as clinical variables: age, gender, arterial hypertension (HTA), tobacco, hyperlipidemia (HLP), obesity (BMI), fibrinogen and diabetes mellitus. The risk factors score was calculated as x/8. Special focus was given to pts with HTA (n=183) who were divided in two subgroups; isolated systolic HTA and systolic/diastolic HTA.</p>
<p>Results: The study included a total of 311 pts, 207 males and 104 females, average age of 64 &#x00B1;11.2 years. Combination of IFP + CAD was registered in 124 pts, with multiple risk factors (MRF) score 4.35, IFP+CdA was registered in 78 pts, with MRF score 4.51, and IFP+CAD+CdA in 109 pts, with MRF score 4.59. HTA was present in 132 pts (42.4%, p&lt;0.01), 86 males and 48 females, with the average age 67.8&#x00B1;12.9. Isolated systolic HTA was registered in 84 pts (63.6%), and systolic/diastolic HTA in 48 pts (36.4%). There was a significant relation between the IFP+CAD pts and isolated systolic HTA, r=.81, p&lt;0.001 and borderline significant relation between IFP+CAD+CdA pts and systolic/diastolic HTA, r=42, p=0.07.</p>
<p>Conclusions: (1) We found a clear link between the PolyAthD and elevated MRF score (r=.64, p&lt;0.01), especially clinical variables HTA (p&lt;0.01) and tobacco (p&lt;0.01). (2) We established a borderline relation rank between dual disease (IFP+CAD and IFP+CdA) and MRF score (r=.46, p&lt;0.05), (3) There was a statistically significant relation between IFP+CAD patients and isolated systolic HTA, r=.81, p&lt;0.001, and a non-significant relation between IFP+CAD and IFP+CAD+CdA disease and systolic/diastolic HTA, r=36, p=0.9.</p>
</body>
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