Complex percutaneous coronary interventions are very common in everyday practice. This type of interventions could not be performed without knowledge of technical aspects of new generation drug eluting stents (DES). There are growing number of publications that new generation DES is more successful in treatment of complex lesions then old generation with better short and long term outcome. (1) Randomized controlled trials on results of percutaneous interventions in complex lesions are crucial in establishing of appropriate treatment for this very challenging group of patients. Results from interventional registries such as Swedish SCAAR registry are very valuable for every day practice.