Objective: The aims of this study were to evaluate atrial electromechanical delay (AEMD) of patients with chronic obstructive pulmonary disease (COPD) in acute and stable periods (1-3) and echocardiographic changes of these patients.

Patients and Methods: A prospective cross-sectional study. Setting: Kars Harakani State Hospital Subjects: 45(22 females, 23 males) patients with acute COPD exacerbation and the control group was stable period of the same patients. Interventions: The first echocardiography was performed in the first 24 hours. The second echocardiographic examination was performed after 3-month. Main outcome measures: Atrial conduction times and systolic-diastolic functions of the right-left heart were evaluated conventional and tissue Doppler Imaging. Plasma levels of CAR and other inflammatory markers were recorded. Statistical analysis was carried out using SPSS software.

Results: At the end of 3-month, lateral/tricuspid, lateral/mitral and septal AEMD were significantly reduced; right ventricle basal, mid and vertical diameters, tricuspid annular plane systolic excursion, Amax tricuspid, tricuspid regurgitant velocity, systolic pulmonary arterial pressure and systolic motion tricuspid; left atrium diameter, left ventricle end-diastolic diameter, interventricular septum thickness, mitral Ea/Aa ratio, systolic motion mitral, systolic motion septal and heart rate differed; CRP, CAR, and neutrophil to lymphocyte ratio were significantly reduced.