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<article article-type="abstract" dtd-version="1.0" xml:lang="en" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">CC</journal-id>
<journal-id journal-id-type="nlm-ta">Cardiol Croat</journal-id>
<journal-title-group>
<journal-title>Cardiologia Croatica</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Cardiol. Croat.</abbrev-journal-title>
</journal-title-group>
<issn pub-type="ppub">1848-543X</issn>
<issn pub-type="epub">1848-5448</issn>
<publisher><publisher-name>Croatian Cardiac Society</publisher-name></publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">CC 2021 16_9-10_295-6</article-id>
<article-id pub-id-type="doi">10.15836/ccar2021.295</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Aortic valve / treatment challenges</subject></subj-group>
<subj-group subj-group-type="subheading"><subject>Extended Abstract</subject></subj-group>
</article-categories>
<title-group>
<article-title>Vascular closure during transcatheter aortic valve implantation: Literature review and experience from University Hospital Centre Split</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9882-9145</contrib-id><name><surname>Kristi&#x0107;</surname><given-names>Ivica</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9272-6906</contrib-id><name><surname>Mateti&#x0107;</surname><given-names>Andrija</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1">*</xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6639-5971</contrib-id><name><surname>Runji&#x0107;</surname><given-names>Frane</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1399-3406</contrib-id><name><surname>Crn&#x010D;evi&#x0107;</surname><given-names>Nikola</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2700-2121</contrib-id><name><surname>Zanchi</surname><given-names>Jak&#x0161;a</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7269-8944</contrib-id><name><surname>Bunc</surname><given-names>Matja&#x017E;</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib>
<aff id="aff1"><label>1</label><institution>University Hospital Centre Split</institution>, <addr-line>Split</addr-line>, <country country="hr">Croatia</country></aff>
<aff id="aff2"><label>2</label><institution>University Medical Centre Ljubljana</institution>, <addr-line>Ljubljana</addr-line>, <country country="si">Slovenia</country></aff>
</contrib-group>
<author-notes>
<corresp id="cor1"><label>*</label>ADDRESS FOR CORRESPONDENCE: Andrija Mateti&#x0107;, Klini&#x010D;ki bolni&#x010D;ki centar Split, Spin&#x010D;i&#x0107;eva 1, &#x2028;HR-21000 Split, Croatia. / Phone: +385-98-954-6455 / E-mail: <email xlink:href="andrija.matetic@gmail.com">andrija.matetic@gmail.com</email></corresp></author-notes>
<pub-date pub-type="epub-ppub"><month>09</month><year>2021</year></pub-date>
<volume>16</volume>
<issue>9-10</issue>
<fpage>295</fpage>
<lpage>296</lpage>
<history>
<date date-type="received"><day>30</day><month>07</month><year>2021</year></date>
<date date-type="accepted"><day>05</day><month>08</month><year>2021</year></date>
</history>
<permissions>
<copyright-year>2021</copyright-year>
<copyright-holder>Croatian Cardiac Society</copyright-holder>
</permissions>
<kwd-group kwd-group-type="author"><title>KEYWORDS: </title><kwd>vascular closure device</kwd><kwd>transcatheter aortic valve implantation</kwd><kwd>vascular access</kwd></kwd-group>
</article-meta>
</front>
<body>
<p><bold>Background and Aims</bold>: Vascular closure devices (VCDs) have emerged as a routine method for vascular management. Their evolution allowed for further progress and development of interventional cardiology irrespective of the increased frailty of the treated population (<xref ref-type="bibr" rid="r1"><italic>1</italic></xref>). This short review aims to present available VCDs and describe the most utilized regimes in everyday practice. In addition, we aimed to present a VCDs protocol at the University Hospital Centre Split.</p>
<p><bold>Materials and Methods</bold>: A literature search in the PubMed database was conducted yielding a total of 2,380 research articles in the period of 1975 to 2021. Out of these, 246 articles were review articles. A significant positive trend in the number of published articles was observed across the years (<xref ref-type="fig" rid="f1"><bold>Figure 1</bold></xref>).</p>
<fig id="f1" position="float" fig-type="figure"><label>Figure 1</label><caption><p>Overview of the indexed publications focused on vascular closure devices over the years.</p></caption><graphic xlink:href="CC202116_9-10_295-6-f1"></graphic></fig>
<p><bold>Results</bold>: Different types of VCDs exist according to the closure mechanism. Suture-based VCDs include Abbott Perclose ProGlide and Abbott Prostar XL. Plug-based VCDs encompass Terumo Angio-Seal, Terumo FemoSeal, Cordis MynxGrip, Teleflex Manta, Vivasure Medical PerQSeal, and InSeal Medical InSeal (<xref ref-type="bibr" rid="r2"><italic>2</italic></xref>). The mechanism of vascular closure by both suture- and plug-based VCDs is presented in <xref ref-type="fig" rid="f2"><bold>Figure 2</bold></xref>. Large bore access often requires a combination of the different types of VCDs, and their utilization is literally limitless, depending on the center preferences. Among different options, the most utilized vascular closure method at the University Hospital Centre Split during transcatheter aortic valve replacement (TAVR) combines Abbott Perclose ProGlide and Terumo Angio-Seal allowing for adequate closure and vascular management (<xref ref-type="bibr" rid="r3"><italic>3</italic></xref>). After the TAVR finalization, the percutaneous sutures are tightened around an 8 French sheath, followed by the insertion of the Terumo Angio-Seal device according to standards.</p>
<fig id="f2" position="float" fig-type="figure"><label>Figure 2</label><caption><p>Overview and mechanism of action of different vascular closure devices.</p></caption><graphic xlink:href="CC202116_9-10_295-6-f2"></graphic></fig>
<p><bold>Conclusions</bold>: In conclusion, VCDs represent a modern ubiquitary method for vascular access management, enabling safer and comfortable procedures in a wider patient population. Research on VCDs has substantially increased in recent years. Utilized regimes depend on the access size and center preferences.</p>
</body>
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<ref-list>
<title>LITERATURE</title>
<ref id="r1"><label>1</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Dauerman</surname><given-names>HL</given-names></name></person-group>. <article-title>Rewriting the history of vascular closure devices.</article-title> <source>EuroIntervention</source>. <year>2014</year> June;<volume>10</volume>(<issue>2</issue>):<fpage>175</fpage>&#x2013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.4244/EIJV10I2A29</pub-id><pub-id pub-id-type="pmid">24952054</pub-id></mixed-citation></ref>
<ref id="r2"><label>2</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Noori</surname><given-names>VJ</given-names></name><name><surname>Eldrup-J&#x00F8;rgensen</surname><given-names>J</given-names></name></person-group>. <article-title>A systematic review of vascular closure devices for femoral artery puncture sites.</article-title> <source>J Vasc Surg</source>. <year>2018</year> September;<volume>68</volume>(<issue>3</issue>):<fpage>887</fpage>&#x2013;<lpage>99</lpage>. <pub-id pub-id-type="doi">10.1016/j.jvs.2018.05.019</pub-id><pub-id pub-id-type="pmid">30146036</pub-id></mixed-citation></ref>
<ref id="r3"><label>3</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ko</surname><given-names>TY</given-names></name><name><surname>Kao</surname><given-names>HL</given-names></name><name><surname>Liu</surname><given-names>YJ</given-names></name><name><surname>Yeh</surname><given-names>CF</given-names></name><name><surname>Huang</surname><given-names>CC</given-names></name><name><surname>Chen</surname><given-names>YH</given-names></name><etal/></person-group> <article-title>Intentional combination of ProGlide and Angio-Seal for femoral access haemostasis in transcatheter aortic valve replacement.</article-title> <source>Int J Cardiol</source>. <year>2019</year> October 15;<volume>293</volume>:<fpage>76</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1016/j.ijcard.2019.05.055</pub-id><pub-id pub-id-type="pmid">31155328</pub-id></mixed-citation></ref>
</ref-list>
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</article>
