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<article article-type="abstract" dtd-version="1.0" xml:lang="en" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">CC</journal-id>
<journal-id journal-id-type="nlm-ta">Cardiol Croat</journal-id>
<journal-title-group>
<journal-title>Cardiologia Croatica</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Cardiol. Croat.</abbrev-journal-title>
</journal-title-group>
<issn pub-type="ppub">1848-543X</issn>
<issn pub-type="epub">1848-5448</issn>
<publisher><publisher-name>Croatian Cardiac Society</publisher-name></publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">CC 2022 17_9-10_159-60</article-id>
<article-id pub-id-type="doi">10.15836/ccar2022.159</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Extended Abstract</subject></subj-group>
<subj-group subj-group-type="subheading"><subject>Acute coronary syndromes</subject></subj-group>
</article-categories>
<title-group>
<article-title>Diagnostic problem in acute infarction and vasospastic angina pectoris</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2360-5793</contrib-id><name><surname>Horvat</surname><given-names>Davor</given-names></name><xref ref-type="corresp" rid="cor1">*</xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6309-1793</contrib-id><name><surname>Grman Fanfani</surname><given-names>Andrea</given-names></name></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6178-0555</contrib-id><name><surname>Kasuni&#x0107; Jeli&#x0107;</surname><given-names>Morana</given-names></name></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7676-6470</contrib-id><name><surname>Al Rajabi</surname><given-names>Kamal</given-names></name></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6052-2503</contrib-id><name><surname>Do&#x0161;en</surname><given-names>Andrej</given-names></name></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6658-0931</contrib-id><name><surname>Lipov&#x0161;&#x0107;ak</surname><given-names>Ronald</given-names></name></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4564-602X</contrib-id><name><surname>Jeli&#x0107;</surname><given-names>Dario</given-names></name></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5185-3981</contrib-id><name><surname>Kal&#x010D;ina Uravi&#x0107;</surname><given-names>Lorena</given-names></name></contrib>
<aff id="aff1"><institution>Karlovac General Hospital, Karlovac</institution>, <country country="hr">Croatia</country></aff>
</contrib-group>
<author-notes>
<corresp id="cor1"><label>*</label>ADDRESS FOR CORRESPONDENCE: Davor Horvat, Op&#x0107;a bolnica Karlovac, Andrije &#x0160;tampara 3, HR-47000 Karlovac, Croatia. / Phone: +385-98-9629-570 / E-mail: <email xlink:href="davor.horvat@ka.t-com.hr">davor.horvat@ka.t-com.hr</email></corresp></author-notes>
<pub-date pub-type="epub-ppub"><month>11</month><year>2022</year></pub-date>
<volume>17</volume>
<issue>9-10</issue>
<fpage>159</fpage>
<lpage>160</lpage>
<history>
<date date-type="received"><day>04</day><month>11</month><year>2022</year></date>
<date date-type="accepted"><day>10</day><month>11</month><year>2022</year></date>
</history>
<permissions>
<copyright-year>2022</copyright-year>
<copyright-holder>Croatian Cardiac Society</copyright-holder>
</permissions>
<kwd-group kwd-group-type="author"><title>KEYWORDS: </title><kwd>acute infarction</kwd><kwd>vasospastic angina pectoris</kwd><kwd>electrocardiogram</kwd><kwd>percutaneous coronary intervention</kwd></kwd-group>
</article-meta>
</front>
<body>
<p><bold>Case report</bold>: 79-year-old patient comes to the Emergency Department of Karlovac General Hospital, where he presented with chest pains immediately before arriving at the hospital. 12-lead electrocardiogram (ECG) shows inferior and anterolateral acute ST-elevation myocardial infarction (STEMI) (<xref ref-type="fig" rid="f1"><bold>Figure 1</bold></xref>). He was referred to the Percutaneous Coronary Intervention Network (Sestre Milosrdnice University Hospital Center, Zagreb) where, after emergency coronary angiography, all three epicardial coronary arteries were shown without hemodynamically significant stenoses, with screening at the LAD/D1 bifurcation, which would correspond to the site of a spontaneously reperfused thrombus. The following day, he was returned to the home institution. On ECG: sinus rhythm with ventricular rate 63/min, amputated R inferiorly, q from V1-6 (<xref ref-type="fig" rid="f2"><bold>Figure 2</bold></xref>). Echocardiography: akinesia of the distal 2/3 septum, anterior wall and apex with consequent left ventricular ejection fraction 40%. During the stay, he is treated with low molecular weight heparin, antiplatelet, antihypertensive, and other symptomatic therapy. In the Holter ECG: transient ST elevation is verified in all three leads, which corresponds to the inferior and anterolateral region in the 12-channel ECG (<xref ref-type="fig" rid="f3"><bold>Figure 3</bold></xref>). This event was not accompanied by significant angina pains or an increase in troponin. ECG at discharge: sinus rhythm 52/min., anterior ischemia, and minor residual anterior ST elevation (<xref ref-type="fig" rid="f4"><bold>Figure 4</bold></xref>). Discharge diagnoses: Inferoposterior and anteroseptolateral STEMI, Spontaneous reperfusion, Unstable angina pectoris (vasospastic). Therapy at discharge: aspirin, clopidogrel, atorvastatin, trimetazidine, diltiazem, perindopril.</p>
<fig id="f1" position="float" fig-type="figure"><label>FIGURE 1</label><caption><p>Electrocardiogram on arrival at the Emergency Department shows significant elevation of the ST-segment in the inferior and anterolateral leads.</p></caption><graphic xlink:href="CC202217_9-10_159-60-f1"></graphic></fig>
<fig id="f2" position="float" fig-type="figure"><label>FIGURE 2</label><caption><p>Electrocardiogram on the second day of hospital stay after coronary angiography and spontaneous reperfusion shows amputated R wave inferiorly and q wave in all precordial leads.</p></caption><graphic xlink:href="CC202217_9-10_159-60-f2"></graphic></fig>
<fig id="f3" position="float" fig-type="figure"><label>FIGURE 3</label><caption><p>Electrocardiogram from a three-channel holter recording with significant elevation of the ST-segment in all three leads.</p></caption><graphic xlink:href="CC202217_9-10_159-60-f3"></graphic></fig>
<fig id="f4" position="float" fig-type="figure"><label>FIGURE 4</label><caption><p>Electrocardiogram at discharge from the hospital shows a negative T wave and minor residual ST segment elevation in all precordial leads.</p></caption><graphic xlink:href="CC202217_9-10_159-60-f4"></graphic></fig>
<p><bold>Conclusion</bold>: The occurrence of ST-segment elevation in ECG as part of an acute myocardial infarction is a common finding in STEMI and indicates the need for urgent access to the patient. The appearance of spontaneous reperfusion in the infarct is a welcome natural revascularization when the performance of the PCI procedure is mostly no longer necessary. (<xref ref-type="bibr" rid="r1"><italic>1</italic></xref>-<xref ref-type="bibr" rid="r3"><italic>3</italic></xref>) Although spontaneous reperfusion still indicates a thrombotic cause of infarction, transient ST-segment elevation in the ECG caused by vasospasm can rarely be seen at these moments. In order to ultimately reduce additional complications and mortality, a proper and timely approach to diagnosis and therapy in these patients is extremely important.</p>
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<ref-list>
<title>LITERATURE</title>
<ref id="r1"><label>1</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kaya</surname><given-names>&#x00C7;</given-names></name><name><surname>Altay</surname><given-names>S</given-names></name></person-group>. <article-title>An extreme case of vasospastic angina mimicking acute STEMI: Severe threevessel disease with critical stenoses.</article-title> <source>Anatol J Cardiol</source>. <year>2019</year> June;<volume>21</volume>(<issue>6</issue>):<fpage>347</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.14744/AnatolJCardiol.2019.74171</pub-id><pub-id pub-id-type="pmid">31142724</pub-id></mixed-citation></ref>
<ref id="r2"><label>2</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Prinzmetal</surname><given-names>M</given-names></name><name><surname>Kennamer</surname><given-names>R</given-names></name><name><surname>Merliss</surname><given-names>R</given-names></name><name><surname>Wada</surname><given-names>T</given-names></name><name><surname>Bor</surname><given-names>N</given-names></name></person-group>. <article-title>Angina pectoris. I. A variant form of angina pectoris; preliminary report.</article-title> <source>Am J Med</source>. <year>1959</year> September;<volume>27</volume>:<fpage>375</fpage>&#x2013;<lpage>88</lpage>. <pub-id pub-id-type="doi">10.1016/0002-9343(59)90003-8</pub-id><pub-id pub-id-type="pmid">14434946</pub-id></mixed-citation></ref>
<ref id="r3"><label>3</label><mixed-citation publication-type="book">Braunwald E. Heart Disease: A Textbook of Cardiovascular Medicine. 6th ed. Philadelphia: WB Saunders Company; 2001.</mixed-citation></ref>
</ref-list>
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