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<article article-type="abstract" dtd-version="1.0" xml:lang="en" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">CC</journal-id>
<journal-id journal-id-type="nlm-ta">Cardiol Croat</journal-id>
<journal-title-group>
<journal-title>Cardiologia Croatica</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Cardiol. Croat.</abbrev-journal-title>
</journal-title-group>
<issn pub-type="ppub">1848-543X</issn>
<issn pub-type="epub">1848-5448</issn>
<publisher><publisher-name>Croatian Cardiac Society</publisher-name></publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">CC 2022 17_9-10_251</article-id>
<article-id pub-id-type="doi">10.15836/ccar2022.251</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Extended Abstract</subject></subj-group>
<subj-group subj-group-type="subheading"><subject>Cardiovascular prevention and rehabilitation</subject></subj-group>
</article-categories>
<title-group>
<article-title>Individual prescription of exercise as medicine: guidelines-guided or patient based?</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4473-5431</contrib-id><name><surname>Per&#x0161;i&#x0107;</surname><given-names>Viktor</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="aff" rid="aff3"><sup>3</sup></xref><xref ref-type="corresp" rid="cor1">*</xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0379-5235</contrib-id><name><surname>Skro&#x010D;e</surname><given-names>Kristina</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6238-3738</contrib-id><name><surname>Travica Samsa</surname><given-names>Dijana</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9353-0542</contrib-id><name><surname>Kne&#x017E;evi&#x0107;</surname><given-names>Koraljka</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4990-6201</contrib-id><name><surname>Ku&#x017E;et Miokovi&#x0107;</surname><given-names>Irena</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2710-4769</contrib-id><name><surname>Njegovan</surname><given-names>Marina</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6806-2027</contrib-id><name><surname>Premu&#x0161;</surname><given-names>Danijel</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3349-0395</contrib-id><name><surname>Ivani&#x0161;</surname><given-names>Viktor</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<aff id="aff1"><label>1</label><institution>Special Hospital for Medical Rehabilitation of the Heart and Lung Diseases and Rheumatism &#x201C;Thalassotherapia Opatija&#x201D;</institution>, <addr-line>Opatija</addr-line>, <country country="hr">Croatia</country></aff>
<aff id="aff2"><label>2</label><institution>The Faculty of Medicine of the University of Rijeka</institution>, <addr-line>Rijeka</addr-line>, <country country="hr">Croatia</country></aff>
<aff id="aff3"><label>3</label><institution>The Faculty of Dental Medicine and Health of the University of Osijek</institution>, <addr-line>Osijek</addr-line>, <country country="hr">Croatia</country></aff>
<aff id="aff4"><label>4</label><institution>University of Verona</institution>, <addr-line>Verona</addr-line>, <country country="it">Italy</country></aff>
</contrib-group>
<author-notes>
<corresp id="cor1"><label>*</label>ADDRESS FOR CORRESPONDENCE: Viktor Per&#x0161;i&#x0107;, Thalassotherapia Opatija, Ul. Mar&#x0161;ala Tita 188, HR-51410 Opatija, Croatia. / Phone: +385-91-1207-605 / E-mail: <email xlink:href="viktor.persic@ri.t-com.hr">viktor.persic@ri.t-com.hr</email></corresp></author-notes>
<pub-date pub-type="epub-ppub"><month>11</month><year>2022</year></pub-date>
<volume>17</volume>
<issue>9-10</issue>
<fpage>251</fpage>
<lpage>251</lpage>
<history>
<date date-type="received"><day>03</day><month>11</month><year>2022</year></date>
<date><day>10</day><month>11</month><year>2022</year></date>
</history>
<permissions>
<copyright-year>2022</copyright-year>
<copyright-holder>Croatian Cardiac Society</copyright-holder>
</permissions>
<kwd-group kwd-group-type="author"><title>KEYWORDS: </title><kwd>cardiorespiratory fitness</kwd><kwd>exercise</kwd><kwd>health</kwd><kwd>myocardial infarction</kwd></kwd-group>
</article-meta>
</front>
<body>
<p><bold>Introduction:</bold> High intensity interval training (HIIT) is now recognized in international clinical-based exercise guidelines as an appropriate and beneficial adjunct to moderate intensity continuous training. (<xref ref-type="bibr" rid="r1"><italic>1</italic></xref>) Moreover, prescribing precise HIIT intensity based on individual capacities and needs is mandatory to optimize results. However, intensity prescription might encounter some obstacles when it comes to implementing pre-training testing. This study showcases individual exercise prescription in a group of ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) patients to achieve progressive increase of functional capacity and therefore &#x2013; better health and quality of life as primary outcomes.</p>
<p><bold>Patients and Methods:</bold> 16 STEMI and NSTEMI patients (age 58 &#x00B1; 10 years; height 177 &#x00B1; 9 cm; weight 86.8 &#x00B1; 15.4 kg; VO<sub>2</sub>max 19 &#x00B1; 5.3 ml min<sup>-1</sup> kg<sup>-1</sup>) underwent 12 weeks of supervised cycling HIIT (4x4 min at 85-95% of HRmax) 3 times per week. Functional capacity (VO<sub>2</sub>max) and all cardiopulmonary parameters as well as HRmax ware assessed by means of the incremental cardiopulmonary test to exhaustion (CPET) every 4 throughout the training program. Individual training zones were prescribed and adjusted according to the parameters obtained in CPET.</p>
<p><bold>Results:</bold> There was a good correlation (r= 0.67) between the predicted HRmax and measured HRmax at the beginning of the training period but a weak correlation (r=0.43) at the end of a 12-week training program. The absolute improvement in VO<sub>2</sub>peak at the end of the 12-week training was 32% (19.2 &#x00B1; 5.1 vs 25.5 &#x00B1; 4.9 mil min-1 kg-1, P&lt;.001).</p>
<p><bold>Conclusion:</bold> The &#x201C;dose&#x201D; of the exercise can be operationalized and monitored using a specific indicator (or set of specific indicators) of internal load as proxy. In this regard, to maximize safety in clinical populations, it is mandatory to precisely adjust pre-exercise screening and regular monitoring. Modifying the exercise prescription by carefully adjusting the external load in relation to internal parameters, can define an optimal dose for this group of patients.</p>
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<ref-list>
<title>LITERATURE</title>
<ref id="r1"><label>1</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Taylor</surname><given-names>JL</given-names></name><name><surname>Holland</surname><given-names>DJ</given-names></name><name><surname>Spathis</surname><given-names>JG</given-names></name><name><surname>Beetham</surname><given-names>KS</given-names></name><name><surname>Wisl&#x00F8;ff</surname><given-names>U</given-names></name><name><surname>Keating</surname><given-names>SE</given-names></name><etal/></person-group> <article-title>Guidelines for the delivery and monitoring of high intensity interval training in clinical populations.</article-title> <source>Prog Cardiovasc Dis</source>. <year>2019</year> March-April;<volume>62</volume>(<issue>2</issue>):<fpage>140</fpage>&#x2013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1016/j.pcad.2019.01.004</pub-id><pub-id pub-id-type="pmid">30685470</pub-id></mixed-citation></ref>
</ref-list>
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