Aim: The aim of this study was to make a retrospective analysis of patients admitted to hospital due to endocarditis and their characteristics.

Patients and Methods: In the period of 2 years, from June 2021 to June 2023, medical history of patients hospitalized in Department of Cardiovascular Diseases in University Hospital “Sveti Duh” with the diagnosis of endocarditis were examined.

Results: A total number of 9 patients were identified with the diagnosis of endocardits. 6 were women and 3 were men. The average age was 66 years (38-83 y). The average hospitalization days was 35 (1-62 days). 4 patients had endocarditis of the native mitral valve, 4 of the native aortic valve, 1 of the tricuspid valve and only one had it on the artificial valve. 6 patients were discharged home after antibiotic therapy, two underwent surgery and one died. The most common causative agents were Streptococcus (aureus, pneumoniae, alactolyticus) and Staphylococcus (epidermidis, capitis aureus), only one patient had Enterococcus faecalis.

Conclusion: According to our data, endocarditis of the native mitral valve in middle-aged and elderly women is most often. The Streptococcus and Staphylococcus sp are the most common causative agents. Antibiotics are generally sufficient to treat endocarditis (1, 2).