<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "http://jats.nlm.nih.gov/publishing/1.0/JATS-journalpublishing1.dtd">
<article article-type="abstract" dtd-version="1.0" xml:lang="en" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">CC</journal-id>
<journal-id journal-id-type="nlm-ta">Cardiol Croat</journal-id>
<journal-title-group>
<journal-title>Cardiologia Croatica</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Cardiol. Croat.</abbrev-journal-title>
</journal-title-group>
<issn pub-type="ppub">1848-543X</issn>
<issn pub-type="epub">1848-5448</issn>
<publisher><publisher-name>Croatian Cardiac Society</publisher-name></publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">CC 2024 19_11-12_468</article-id>
<article-id pub-id-type="doi">10.15836/ccar2024.468</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Extended Abstract</subject></subj-group>
<subj-group subj-group-type="subheading"><subject>Valvular heart disease</subject></subj-group>
</article-categories>
<title-group>
<article-title>Minimally invasive aortic valve replacement</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9644-9739</contrib-id><name><surname>&#x0160;u&#x0161;njar</surname><given-names>Dubravka</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1">*</xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6602-699X</contrib-id><name><surname>Varvodi&#x0107;</surname><given-names>Josip</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5955-0275</contrib-id><name><surname>Bari&#x0107;</surname><given-names>Davor</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2740-4067</contrib-id><name><surname>Uni&#x0107;</surname><given-names>Daniel</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5690-9924</contrib-id><name><surname>Ku&#x0161;urin</surname><given-names>Marko</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4304-1852</contrib-id><name><surname>Gjeorgjievska</surname><given-names>Savica</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6245-5508</contrib-id><name><surname>&#x0160;estan</surname><given-names>Gloria</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9796-736X</contrib-id><name><surname>Sli&#x0161;kovi&#x0107;</surname><given-names>Nikola</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7735-6721</contrib-id><name><surname>Rude&#x017E;</surname><given-names>Igor</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib>
<aff id="aff1"><label>1</label><institution>Dubrava University Hospital</institution>, <addr-line>Zagreb</addr-line>, <country country="hr">Croatia</country></aff>
<aff id="aff2"><label>2</label><institution>University of Zagreb</institution>, <institution content-type="dept">School of Medicine</institution>, <addr-line>Zagreb</addr-line>, <country country="hr">Croatia</country></aff>
</contrib-group>
<author-notes>
<corresp id="cor1"><label>*</label>ADDRESS FOR CORRESPONDENCE: Dubravka &#x0160;u&#x0161;njar, Klini&#x010D;ka bolnica Dubrava, Avenija Gojka &#x0160;u&#x0161;ka 6, HR-10000 Zagreb, Croatia. / Phone: +385-99-2904-019 / E-mail: <email xlink:href="dubravka.susnjar@gmail.com">dubravka.susnjar@gmail.com</email></corresp></author-notes>
<pub-date date-type="pub" publication-format="electronic"><month>11</month><year>2024</year></pub-date>
<pub-date date-type="pub" publication-format="print"><month>11</month><year>2024</year></pub-date>
<volume>19</volume>
<issue>11-12</issue>
<fpage>468</fpage>
<lpage>468</lpage>
<history>
<date date-type="received"><day>13</day><month>10</month><year>2024</year></date>
<date><day>31</day><month>10</month><year>2024</year></date>
</history>
<permissions>
<copyright-statement>Croatian Cardiac Society</copyright-statement>
<copyright-year>2024</copyright-year>
<copyright-holder>Croatian Cardiac Society</copyright-holder>
</permissions>
<kwd-group kwd-group-type="author"><title>KEYWORDS: </title><kwd>aortic stenosis</kwd><kwd>minimally invasive cardiac surgery</kwd><kwd>ministernotomy,</kwd></kwd-group>
</article-meta>
</front>
<body>
<p>Calcifying aortic stenosis is the most common heart valve disease and important cause of cardiovascular morbidity and mortality. The gold standard for treatment of aortic stenosis is surgical replacement of the aortic valve through sternotomy. A minimally invasive approach through an upper ministernotomy, results in a reduction of perioperative complications, especially in obese patients, including less postoperative drainage, a lower frequency of postoperative atrial fibrillation, reduces the number of days patient stays in the intensive care unit, faster recovery, easier verticalization, and ultimately faster discharge from the hospital.</p>
<p>Upper ministernotomy can be performed through the 3rd or 4th intercostal space, and the skin incision, in our institution, measures 6-10 cm on average. (<xref ref-type="fig" rid="f1"><bold>Figure 1</bold></xref>). In the early postoperative course, with the application of intercostal block due to minor pain, it was possible to quickly separate the patient from the machine for mechanical ventilation (extubation) and place the patient in a semi-sitting position. On the first postoperative day, if the drainage is below 200 mL, the patients are transferred to the Department of Cardiac Surgery and verticalized on the same day. Due to the smaller wound, the possibility of developing infection is reduced, especially in the lower part (xiphoid) where infections occur most often. In our institution, aortic valve replacement through ministernotomy is amounted to 14% of the total number of classical surgical aortic valve replacement over the last 5 years (<xref ref-type="fig" rid="f2"><bold>Figure 2</bold></xref>). The goal of minimally invasive surgery is to preserve the integrity of the sternum, whitch leads to a reduction of postoperative complications. But we must also mention the shortcomings. Reduced visualization of the surgical field and the valve, may result in the implantation of a suboptimal prosthesis size and increased rate of paravalvular regurgitation. (<xref ref-type="bibr" rid="r1"><italic>1</italic></xref>, <xref ref-type="bibr" rid="r2"><italic>2</italic></xref>)</p>
<fig id="f1" position="float" fig-type="figure"><label>FIGURE 1</label><caption><p>Upper ministernotomy.</p></caption><graphic xlink:href="CC202419_11-12_468-f1"></graphic></fig>
<fig id="f2" position="float" fig-type="figure"><label>FIGURE 2</label><caption><p>Comparison of aortic valve replacements and minimally invasive aortic valve replacement with patient percentage by year. AVR = aortic valve replacements; MINI AVR = minimally invasive aortic valve replacement</p></caption><graphic xlink:href="CC202419_11-12_468-f2"></graphic></fig>
<p>The minimally invasive approach represents a significant benefit for the postoperative recovery of the patient and therefore it should become the standard for aortic valve operations.</p>
</body>
<back>
<ref-list>
<title>LITERATURE</title>
<ref id="r1"><label>1</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Hancock</surname><given-names>HC</given-names></name><name><surname>Maier</surname><given-names>RH</given-names></name><name><surname>Kasim</surname><given-names>A</given-names></name><name><surname>Mason</surname><given-names>J</given-names></name><name><surname>Murphy</surname><given-names>G</given-names></name><name><surname>Goodwin</surname><given-names>A</given-names></name><etal/></person-group> <article-title>Mini-sternotomy versus conventional sternotomy for aortic valve replacement: a randomised controlled trial.</article-title> <source>BMJ Open</source>. <year>2021</year> January 29;<volume>11</volume>(<issue>1</issue>):<elocation-id>e041398</elocation-id>. <pub-id pub-id-type="doi">10.1136/bmjopen-2020-041398</pub-id><pub-id pub-id-type="pmid">33514577</pub-id></mixed-citation></ref>
<ref id="r2"><label>2</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kirmani</surname><given-names>BH</given-names></name><name><surname>Akowuah</surname><given-names>E</given-names></name></person-group>. <article-title>Minimal Access Aortic Valve Surgery.</article-title> <source>J Cardiovasc Dev Dis</source>. <year>2023</year> June 30;<volume>10</volume>(<issue>7</issue>):<fpage>281</fpage>. <pub-id pub-id-type="doi">10.3390/jcdd10070281</pub-id><pub-id pub-id-type="pmid">37504537</pub-id></mixed-citation></ref>
</ref-list>
</back>
</article>
