<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "JATS-journalpublishing1.dtd">
<article article-type="abstract" dtd-version="1.0" xml:lang="en" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">CC</journal-id>
<journal-id journal-id-type="nlm-ta">Cardiol Croat</journal-id>
<journal-title-group>
<journal-title>Cardiologia Croatica</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Cardiol. Croat.</abbrev-journal-title>
</journal-title-group>
<issn pub-type="ppub">1848-543X</issn>
<issn pub-type="epub">1848-5448</issn>
<publisher><publisher-name>Croatian Cardiac Society</publisher-name></publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">CC 2024 19_3-4_131-2</article-id>
<article-id pub-id-type="doi">10.15836/ccar2024.131</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Extended Abstract</subject></subj-group>
<subj-group subj-group-type="subheading"><subject>Cardiac arrhythmias, pacing and electrophysiology</subject></subj-group>
</article-categories>
<title-group>
<article-title>Substrate-based ablation of idiopathic atypical atrial flutter: a case report</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5533-7215</contrib-id><name><surname>Mustapi&#x0107;</surname><given-names>Vito</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1">*</xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9634-9511</contrib-id><name><surname>Szavits Nossan</surname><given-names>Janko</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8317-2219</contrib-id><name><surname>Barbari&#x0107;</surname><given-names>Lucija</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-8257-2624</contrib-id><name><surname>Regvar</surname><given-names>Karlo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7995-1452</contrib-id><name><surname>Kop&#x010D;i&#x0107;</surname><given-names>Iva</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-8266-6755</contrib-id><name><surname>Juri&#x0161;i&#x0107;</surname><given-names>&#x0160;imun</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib>
<aff id="aff1"><label>1</label><institution content-type="dept">Magdalena Clinic for Cardiovascular Disease, Krapinske Toplice, at Faculty of Medicine</institution>, <institution>JJ Strossmayer University in Osijek</institution>, <addr-line>Osijek</addr-line>, <country country="hr">Croatia</country></aff>
<aff id="aff2"><label>2</label><institution>Josip Juraj Strossmayer University of Osijek</institution>, <institution content-type="dept">Faculty of Dental Medicine and Health Osijek</institution>, <addr-line>Osijek</addr-line>, <country country="hr">Croatia</country></aff>
<aff id="aff3"><label>3</label><institution>Biosense webster, Johnson &amp; Johnson S.E., d.o.o.</institution>, <addr-line>Zagreb</addr-line>, <country country="hr">Croatia</country></aff>
</contrib-group>
<author-notes>
<corresp id="cor1"><label>*</label>ADDRESS FOR CORRESPONDENCE: Vito Mustapi&#x0107;, Klinika Magdalena, Ljudevita Gaja 2, HR-49217 Krapinske Toplice, Croatia. / Phone: +385-99-236-0551 / E-mail: <email xlink:href="vito.mustapic@gmail.com">vito.mustapic@gmail.com</email></corresp></author-notes>
<pub-date date-type="pub" publication-format="electronic"><month>11</month><year>2023</year></pub-date>
<pub-date date-type="pub" publication-format="print"><month>11</month><year>2023</year></pub-date>
<volume>19</volume>
<issue>3-4</issue>
<fpage>131</fpage>
<lpage>132</lpage>
<history>
<date date-type="received"><day>21</day><month>10</month><year>2023</year></date>
<date date-type="accepted"><day>27</day><month>10</month><year>2023</year></date>
</history>
<permissions>
<copyright-statement>Croatian Cardiac Society</copyright-statement>
<copyright-year>2023</copyright-year>
<copyright-holder>Croatian Cardiac Society</copyright-holder>
</permissions>
<kwd-group kwd-group-type="author"><title>KEYWORDS: </title><kwd>atypical atrial flutter</kwd><kwd>catheter ablation</kwd><kwd>substrate ablation</kwd></kwd-group>
</article-meta>
</front>
<body>
<p><bold>Introduction</bold>: Atypical atrial flutter usually occurs in the setting of prior ablation or cardiac surgery where iatrogenic scares serve as the electrophysiologic substrate for re-entry. Idiopathic atypical atrial flutter is an uncommon variant. Whether the standard anatomical or substrate ablation approach is the best treatment option for this type of arrhythmia remains a debate (<xref ref-type="bibr" rid="r1"><italic>1</italic></xref>, <xref ref-type="bibr" rid="r2"><italic>2</italic></xref>).</p>
<p><bold>Case report</bold>: A middle-aged female patient with a history of ischemic heart disease and percutaneous coronary intervention, ICD implantation for secondary prevention, and no prior history of atrial fibrillation, cardiac surgery, or ablation presented with new onset persistent atrial flutter (<xref ref-type="fig" rid="f1"><bold>Figure 1</bold></xref>). An electrophysiology study was conducted with entrainment suggesting atypical atrial flutter from the left atrium. 3-dimensional mapping of the left atrium using the Carto 3 system and multipolar catheter (Biosense Webster) was performed, showing a scar with the zone of slow conduction (critical isthmus) on the anterior wall near the roof and the left superior pulmonary vein (<xref ref-type="fig" rid="f2"><bold>Figure 2</bold></xref>). Ablation of critical isthmus terminated tachycardia (<xref ref-type="fig" rid="f3"><bold>Figure 3</bold></xref>). A few additional lesions for substrate ablation were applied avoiding linear anatomical lines. After ablation, tachycardia was non-inducible.</p>
<fig id="f1" position="float" fig-type="figure"><label>FIGURE 1</label><caption><p>12-lead electrocardiogram showing atrial flutter on admission.</p></caption><graphic xlink:href="CC202419_3-4_131-2-f1"></graphic></fig>
<fig id="f2" position="float" fig-type="figure"><label>FIGURE 2</label><caption><p>Coherent mapping of the left atrium with a zone of slow conduction and critical isthmus (black circle) for atypical flutter.</p></caption><graphic xlink:href="CC202419_3-4_131-2-f2"></graphic></fig>
<fig id="f3" position="float" fig-type="figure"><label>FIGURE 3</label><caption><p>Termination of tachycardia during critical isthmus ablation (green arow on the left part and the red circle on the right part of the picture).</p></caption><graphic xlink:href="CC202419_3-4_131-2-f3"></graphic></fig>
<p><bold>Conclusion</bold>: There are still no clear recommendations regarding ablation of atypical atrial flutter and our case highlights the need for an individual approach when considering between anatomical or substrate ablation approaches, thus potentially avoiding excessive ablation lines.</p>
</body>
<back>
<ref-list>
<title>LITERATURE</title>
<ref id="r1"><label>1</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Pott</surname><given-names>A</given-names></name><name><surname>Teumer</surname><given-names>Y</given-names></name><name><surname>Weinmann</surname><given-names>K</given-names></name><name><surname>Baumhardt</surname><given-names>M</given-names></name><name><surname>Schweizer</surname><given-names>C</given-names></name><name><surname>Buckert</surname><given-names>D</given-names></name><etal/></person-group> <article-title>Substrate-based ablation of atypical atrial flutter in patients with atrial cardiomyopathy.</article-title> <source>Int J Cardiol Heart Vasc</source>. <year>2022</year> April 18;<volume>40</volume>:<elocation-id>101018</elocation-id>. <pub-id pub-id-type="doi">10.1016/j.ijcha.2022.101018</pub-id><pub-id pub-id-type="pmid">35495579</pub-id></mixed-citation></ref>
<ref id="r2"><label>2</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Cherian</surname><given-names>TS</given-names></name><name><surname>Supple</surname><given-names>G</given-names></name><name><surname>Smietana</surname><given-names>J</given-names></name><name><surname>Santangeli</surname><given-names>P</given-names></name><name><surname>Nazarian</surname><given-names>S</given-names></name><name><surname>Lin</surname><given-names>D</given-names></name><etal/></person-group> <article-title>Idiopathic Atypical Atrial Flutter Is Associated With a Distinct Atriopathy.</article-title> <source>JACC Clin Electrophysiol</source>. <year>2021</year> September 1;<volume>7</volume>(<issue>9</issue>):<fpage>1193</fpage>&#x2013;<lpage>5</lpage>. <pub-id pub-id-type="doi">10.1016/j.jacep.2021.05.004</pub-id><pub-id pub-id-type="pmid">34332868</pub-id></mixed-citation></ref>
</ref-list>
</back>
</article>
